L-Alaninol (CAS 2749-11-3): A Small Molecule with Big Scientific Value

 L-Alaninol (CAS 2749-11-3): A Small Molecule with Big Scientific Value

Introduction

In the world of research and pharmaceuticals, small molecules often have the biggest impact. One such compound is L-Alaninol (CAS 2749-11-3) — also known as (S)-2-Aminopropan-1-ol. This chiral amino alcohol may look simple on paper, but its applications in organic synthesis, drug development, and biomedical research make it an essential tool for scientists and innovators.

 What is L-Alaninol?

L-Alaninol is a chiral amino alcohol with the molecular formula C₃H₉NO and a molecular weight of 75.11 g/mol. Its structure allows it to act as a building block in creating complex molecules, especially those requiring specific optical orientation.

Depending on its form, it appears as a colorless liquid or crystalline solid. Some key properties include:

  • Boiling point: 174–175 °C
  • Density: around 0.965 g/mL at 25 °C
  • Refractive index: 1.44–1.45
  • Melting point: about –2 °C

These features make it reliable, stable, and widely usable in research laboratories.

 


Applications in Organic Chemistry

The real strength of L-Alaninol lies in its chirality. Chirality refers to a molecule’s ability to exist in two mirror-image forms, and this property is critical in pharmaceuticals and fine chemical synthesis.

Some major uses of L-Alaninol include:

  • Developing chiral auxiliaries for asymmetric synthesis
  • Serving as a ligand in enantioselective catalysis
  • Creating Schiff-base ligands that support metal-catalyzed reactions
  • Producing oxazoline intermediates, which are key in the pharmaceutical industry

In short, L-Alaninol helps chemists achieve precision in synthesis, making it vital for drug development and advanced material research.

 

Biological Potential

While primarily used in chemical synthesis, some research has suggested that L-Alaninol may also exhibit biological activity. Studies point to potential effects like:

  • Slowing down melanoma cell proliferation
  • Increasing enzyme activities such as cytochrome C reductase
  • Enhancing γ-glutamyl transpeptidase activity

Although promising, it’s important to note that L-Alaninol is currently intended for research use only and is not approved for medical or clinical applications.

 

Safety and Storage

Because of its chemical nature, L-Alaninol requires careful handling. It is classified as corrosive and must be managed according to strict lab safety standards.

  • Hazards: May cause burns, skin and eye irritation, and is harmful if inhaled or ingested.
  • Protective measures: Gloves, lab coats, safety goggles, and proper ventilation should always be used.
  • Storage: Best kept in tightly sealed containers, preferably refrigerated at 2–8 °C, away from moisture and direct sunlight.

Following these precautions ensures both researcher safety and compound stability.

 

Why L-Alaninol Matters

Today’s scientific progress depends heavily on precision and innovation. From drug discovery to advanced materials and green chemistry, compounds like L-Alaninol make it possible to create new solutions with accuracy and efficiency.

Its ability to serve as a dependable chiral building block ensures that it remains in steady demand across the pharmaceutical, chemical, and academic sectors.

 

Conclusion

To sum it up, L-Alaninol (CAS 2749-11-3) is more than just a small laboratory compound:

  • It is a powerful chiral amino alcohol with essential roles in organic synthesis.
  • It acts as a key intermediate in pharmaceuticals and fine chemical industries.
  • It shows potential biological effects, though its current use is limited to research.
  • Safe handling and proper storage are crucial for working with this compound.

In the world of chemistry, even the smallest molecules can drive the biggest innovations — and L-Alaninol is a perfect example of that.

 
Pharmaffiliates is recognized worldwide as a trusted partner in the pharmaceutical industry. Specializing in reference standards, impurities, and custom synthesis, the company plays a vital role in supporting research, quality testing, and drug development with a strong commitment to accuracy and compliance.

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